Date: 26 octobre 2020 à 13h00
Presentation: Stylianos Antonarakis
Sujet: Gonadal mosaicism and transmission of genomic variants to the offspring
Référence(s): Xiaoxu Yang et al., … Joseph G. Gleeson, Temporal stability of human sperm mosaic mutations results in life-long threat of transmission to offspring, doi: https://doi.org/10.1101/2020.10.14.339796, Posted in biorxiv 14oct20
Thomas A Sasani, Brent S Pedersen, Ziyue Gao, Lisa Baird, Molly Przeworski, Lynn B Jorde, Aaron R Quinlan, Elife. 2019 Sep 24;8:e46922. doi: 10.7554/eLife.46922., Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation, PMID: 31549960
C STERN, A mosaic of Drosophila consisting of 1X, 2X and 3X tissue and its probable origin by mitotic non-disjunction, Nature 1960 Apr 9;186:179-80. doi: 10.1038/186179b0., PMID: 13834426
